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20% tilmicosin premix

tilmicosin premix (10% or 20%)

 

 

c.a.s. number: 108050-54-0

synonyms: 20-deoxy-20-(3,5-dimethylpiperidin-1-yl)-desmycosin

structural formula

 

molecular formula: c46h80n2o13

molecular weight: 869.15

 

general

1. pharmacodynamics:

tilmicosin is a kind of widely used macrolide antibiotics developed for veterinary use only. it is highly recommended for treatment and prevention of respiratory diseases in cattle, sheep and pigs, associated with pasteurella haemolytica, p. multocida, actinobacillus pleuropneumoniae, mycoplasma species and other microorganisms found sensitive to this compound. its antibacterial action is similar to tylosin.


2. pharmacokinetics:

benefit by the latest microcapsule technique, timilcosin could be capsuled by polyacrylic resin and enteric-soluble material, which ensure timilcosin could be absorbed efficiently by oral administration. compared with the other traditional tilmicosin supply forms (such as tilmicosin powder), micro-capsuled timilcosin hasn’t any irritating taste and smell, while active ingredient is controlled-released from microcapsules into tissues with a good penetration.

 


fig. plasma concentration versus time curve of tilmicosin


precaution:

1. only used for therapy;

2. timicosin has stimulation to eyes and could induce allergic response, so forbid direct contacting.

 

storage:  

1.  sealed and store in a dry and cool place, away from sunlight.

2.  finish using the product soon after it is unsealed.


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