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10% tiamulin fumarate

 

 

c.a.s. number: 55297-96-6

structural formula

 

molecular formula: c32h51no8s

 

indications

tiamulin fumarate is a pleuromutilin antibiotic that is used in veterinary medicine particularly for swine and poultry, and active against gram-positive bacteria, several mycoplasma species and anaerobes, including brachyspira hyodysenteriae. it is also clinically effective in the treatment of swine respiratory disease, dysentery and mycoplasmal arthritis. it could also be applied for treatment of other diseases that caused by microorganisms found sensitive to this compound. it is soluble in aqueous solution and could be well absorbed by oral administration.


features:

tiamulin fumarate targets the 50s ribosomal subunit of pathogenic bacteria and binds its peptidyl transferase to inhibit the process of protein synthesis. this blocks formation of peptide bonds. tiamulin fumarate premix manufactured by great bio applies latest microcapsule technology that allows effective tiamulin fumarate molecule be capsuled by polyacrylic resin and enteric-soluble material. therefore, microcapsule could ensure tiamulin fumarate could be absorbed efficiently by oral administration without irritating taste and smell. it also allows active ingredient be controlled-released from microcapsules into tissues with a good penetration.

 

fig. appearance of tiamulin fumarate premix and the its photograph under 40x microscope

 

precaution:

1.   only used for therapy;

2.   this product interferes with monensin and salinomycin metabolism, and if the drugs are fed together, they become toxic.

3.   this product can’t be used for horse.

 

storage:  

1.  sealed and store in a dry and cool place, away from sunlight.

2.  finish using the product soon after it is unsealed.


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